


American Duchess River Cruise | Lewis & Clark
Louisville to St. Louis - 9 Days
The Ohio River served as a thrilling avenue of American Discovery. Explorers became heroes, bigger-than-life exploits were transformed into legends, and American identity was forever tied to the West. The wilderness region is just as evocative today with an abundance of history to explored. Delve into the early days of American exploration and acquaint yourself with the heroic Lewis and Clark Expedition. Special guest historians will be onboard to provide you with a sense of the challenges and triumphs that the nation's early pioneers faced.
Cruise Information: Louisville to St. Louis
Cruise Schedule | Destination |
---|---|
Day 1: | Louisville, KY |
Day 2: | Louisville, KY |
Day 3: | Brandenburg, KY |
Day 4: | Owensboro, KY |
Day 5: | Paducah, KY |
Day 6: | Cape Girardeau, MO |
Day7: | Chester, IL |
Day 8: | River Cruising |
Day 9: | St. Louis, MO - Disembark 8:00 AM |
Louisville to St. Louis River Cruise Highlights
- Churchill Downs
- Kentucky Bourbon Region
- Quaint Towns
- Scenic River Valley H Underground Railroad History
- Steamboat Heritage and Museums
- St. Louis Gateway Arch
- Lewis and Clark Corps of Discovery-Themed Enrichment
Cruise Themes

Lewis & Clark
Discover how the Ohio River served as a thrilling avenue of American discovery, delve into the early days of American exploration, and get acquainted with the courageous pioneers.
One-stop shopping - Book complete cruise vacations with flights, transfers,
pre- and post-cruise stays, onboard accommodations, activities and more
For Cruise Dates, More Itineraries and Bookings
Call Our Dedicated Cruise Desk at
877-287-2835
pre- and post-cruise stays, onboard accommodations, activities and more
For Cruise Dates, More Itineraries and Bookings
Call Our Dedicated Cruise Desk at
877-287-2835
Not responsible for errors or omissions. [Pleasant Holidays acts only as an agent for the various travel providers shown above.]