American Duchess Steamboat
American Duchess Steamboat
Paddle Wheel American Queen Steamboat

American Duchess River Cruise | Lewis & Clark
Pittsburgh to Louisville - 9 Days

The Ohio River served as a thrilling avenue of American Discovery. Explorers became heroes, bigger-than-life exploits were transformed into legends, and American identity was forever tied to the West. The wilderness region is just as evocative today with an abundance of history to explored. Delve into the early days of American exploration and acquaint yourself with the heroic Lewis and Clark Expedition.

Cruise Information: Pittsburgh to Louisville

Pittsbugh, PA

X American Duchess New Orleans to Memphis Itinerary Map

American Duchess Pittsburgh to Louisville Cruise Itinerary

Cruise Schedule Destination
Day 1: Pittsburgh, PA - Hotel Stay
Day 2: Pittsburgh, PA- Depart 5:00 PM
Day 3: Wheeling, WV
Day 4: Marietta, OH
Day 5: Huntington, WV
Day 6: Augusta, KY
Day7: Cincinnati, OH
Day 8: Madison, IN
Day 9: Louisville, KY - Disembark 8:00 AM

Pittsburgh to Louisville River Cruise Highlights

  • Scenic River Valley
  • uaint Towns
  • Local Boutiques
  • Underground Railroad History
  • Steamboat Heritage and Museums
  • Lewis and Clark Corps of Discovery-Themed Enrichment

Cruise Themes

Lewis and Clark Monument

Lewis & Clark

Discover how the Ohio River served as a thrilling avenue of American discovery, delve into the early days of American exploration, and get acquainted with the courageous pioneers.

One-stop shopping - Book complete cruise vacations with flights, transfers,
pre- and post-cruise stays, onboard accommodations, activities and more
For Cruise Dates, More Itineraries and Bookings
Call Our Dedicated Cruise Desk at

Not responsible for errors or omissions. [Pleasant Holidays acts only as an agent for the various travel providers shown above.]